Minnesota at Buffalo 7:00 PM ET
Coming off a highly successful West Coast road trip, the Buffalo Sabres return to home ice on Wednesday to face the Minnesota Wild, when they likely will welcome back their leading goal-scorer.
St. Louis at New Jersey 7:00 PM ET
Jim Montgomery made an immediate impact with the St. Louis Blues after replacing Drew Bannister as head coach, earning a 5-2 road victory over the New York Rangers in his debut.
NY Rangers at Carolina 7:00 PM ET
While the Carolina Hurricanes are putting themselves in strong position to eventually secure home-ice advantage in the postseason, the New York Rangers appear to be a shell of the squad that won the teams' second-round playoff series last season in six games.
Calgary at Detroit 7:30 PM ET
The Detroit Red Wings have wallowed in mediocrity during the first month and a half of the season, which is not conducive to ending an eight-year playoff drought.
Washington at Tampa Bay 7:30 PM ET
The Tampa Bay Lightning suddenly found their mojo Monday night against the Colorado Avalanche and will look to keep the offense thriving when they host the Washington Capitals Wednesday night.
Toronto at Florida 7:30 PM ET
The Toronto Maple Leafs have won four straight games. The Florida Panthers have lost four straight games.
Boston at NY Islanders 7:30 PM ET
For teams outside of the NHL playoff picture, American Thanksgiving is about the time to begin worrying about the standings.
Vancouver at Pittsburgh 7:30 PM ET
The Vancouver Canucks will put their road winning streak on the line when they visit the Pittsburgh Penguins on Wednesday night.
Montreal at Columbus 7:30 PM ET
The Columbus Blue Jackets will put their three-game winning streak on the line Wednesday night when they host the Montreal Canadiens.
Philadelphia at Nashville 8:00 PM ET
The Philadelphia Flyers will aim to move on from a missed opportunity when they visit the Nashville Predators on Wednesday night.
Dallas at Chicago 8:30 PM ET
The Dallas Stars and Chicago Blackhawks haven't been very good at holding leads lately. They'll try to rectify that shortcoming when they meet on Wednesday evening in Chicago.
Vegas at Colorado 10:00 PM ET
They may feel homesick, but the Vegas Golden Knights are rolling so far on their five-game road trip, which they'll wrap up against the Colorado Avalanche on Wednesday night in Denver.
Winnipeg at Los Angeles 10:00 PM ET
The Winnipeg Jets are halfway through their longest road trip of the season, and they like what they've accomplished so far.
Anaheim at Seattle 10:00 PM ET
Some people learn best by doing. For others, it's by watching.
Ottawa at San Jose 10:30 PM ET
The Ottawa Senators will look to make it back-to-back wins when they open a three-game California road trip with a contest against the San Jose Sharks on Wednesday.