Buffalo at Philadelphia 1:00 PM ET
The Buffalo Sabres have been on a roll of late and will look to keep it going when they kick off a three-game road trip with a visit to the Philadelphia Flyers on Saturday.
NY Islanders at Tampa Bay 2:00 PM ET
When it comes to getting into playoff position, the New York Islanders have done themselves no favors over their past three games and could be heading to Florida at the wrong time.
St. Louis at Colorado 4:30 PM ET
The St. Louis Blues are rolling at the right time but face a daunting task to keep their winning streak going.
New Jersey at Minnesota 6:00 PM ET
Minnesota Wild veterans Kirill Kaprizov and Joel Eriksson Ek are getting closer to returning from injuries, but they are not ready yet.
Vegas at Nashville 6:30 PM ET
The Pacific Division-leading Vegas Golden Knights will put their five-game winning streak on the line when they visit the Nashville Predators on Saturday evening.
Columbus at Ottawa 7:00 PM ET
The Ottawa Senators will look to build on their lead in the Eastern Conference wild-card race when they host the Columbus Blue Jackets on Saturday night.
Boston at Detroit 8:00 PM ET
A pair of floundering teams will meet up when the Boston Bruins visit the Detroit Red Wings on Saturday night.
Calgary at Edmonton 10:00 PM ET
The Edmonton Oilers, short-handed without key parts last outing, will seek a huge rebound when they play host to their Battle of Alberta rivals, the Calgary Flames, on Saturday.
NY Rangers at San Jose 10:30 PM ET
Nobody appears to want to earn the last wild-card spot in the Eastern Conference, least of all the New York Rangers.
Dallas at Seattle 10:30 PM ET
The Dallas Stars are spending the weekend in Seattle as they will play two games in three days against the Kraken starting Saturday night. The Stars can officially clinch a playoff spot with a win over the Kraken and a St. Louis Blues' loss to the Colorado Avalanche.