St. Louis at Atlanta 12:15 PM ET
St. Louis center fielder Victor Scott II, an Atlanta native, has made the most of his first trip home as a major-leaguer. On Wednesday, he will try to help the Cardinals win the rubber game of the three-game series against the Braves.
Philadelphia at NY Mets 1:10 PM ET
and not a moment too soon.
Cincinnati at Miami 1:10 PM ET
Sandy Alcantara is off to a rough start this season, but the Miami Marlins are counting on him as they attempt to complete a three-game sweep of the visiting Cincinnati Reds on Wednesday afternoon.
NY Yankees at Cleveland 1:10 PM ET
The Cleveland Guardians succumbed to the New York Yankees in last season's American League Championship Series, but already got a measure of redemption in 2025.
Baltimore at Washington 6:45 PM ET
Dylan Crews will look to extend his hitting streak when the Washington Nationals host the Baltimore Orioles in the middle contest of their three-game series on Wednesday night.
Seattle at Boston 6:45 PM ET
The Boston Red Sox are rolling, and they hope their first baseman might be trending in that direction, too.
LA Dodgers at Chi. Cubs 7:00 PM ET
The Chicago Cubs will look to continue to flex their offensive muscle on Wednesday night when they conclude their season series against the visiting Los Angeles Dodgers.
Colorado at Kansas City 7:40 PM ET
Even when the Colorado Rockies delivered a stunning bases-clearing hit to take a ninth-inning lead, they still couldn't land a road victory.
Toronto at Houston 7:40 PM ET
It took 20 games for the Houston Astros to win consecutive contests for the first time this season.
Chi. White Sox at Minnesota 7:40 PM ET
The only way to break out of an early-season funk is to keep going.
Pittsburgh at LA Angels 9:38 PM ET
Andrew Heaney should feel right at home when he takes the mound for the Pittsburgh Pirates on Wednesday night against the Los Angeles Angels in Anaheim, Calif.
Tampa Bay at Arizona 9:40 PM ET
The Arizona Diamondbacks have found the offensive consistency that the Tampa Bay Rays have been missing recently.
Milwaukee at San Francisco 9:45 PM ET
Two of the most consistent pitchers in recent Major League Baseball history will go head-to-head for the first time when Freddy Peralta and the Milwaukee Brewers continue a four-game road series against Logan Webb and the San Francisco Giants on Wednesday night.
Texas at Athletics 10:05 PM ET
The Texas Rangers hope a change to the lineup that paid huge dividends will continue to be successful when they clash with the Athletics on Wednesday night in the middle game of a three-game American League West series in West Sacramento, Calif.